Home

Recurso repentino Tregua pole exonuclease domain Pelearse maníaco extraño

Distinctive genomic characteristics in POLE/POLD1-mutant cancers can  potentially predict beneficial clinical outcomes in patient
Distinctive genomic characteristics in POLE/POLD1-mutant cancers can potentially predict beneficial clinical outcomes in patient

Mutational processes of distinct POLE exonuclease domain mutants drive an  enrichment of a specific TP53 mutation in colorectal cancer | PLOS Genetics
Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer | PLOS Genetics

Exome sequencing reveals a de novo POLD1 mutation causing phenotypic  variability in mandibular hypoplasia, deafness, progeroid f
Exome sequencing reveals a de novo POLD1 mutation causing phenotypic variability in mandibular hypoplasia, deafness, progeroid f

Clinicopathological and molecular characterization of high-grade  endometrial carcinoma with POLE mutation: a single center study
Clinicopathological and molecular characterization of high-grade endometrial carcinoma with POLE mutation: a single center study

Church Group — Wellcome Centre for Human Genetics
Church Group — Wellcome Centre for Human Genetics

DNA polymerase mutations as drivers of genome instability and cancer
DNA polymerase mutations as drivers of genome instability and cancer

POLE mutations improve the prognosis of endometrial cancer via regulating  cellular metabolism through AMF/AMFR signal transduction | BMC Medical  Genetics | Full Text
POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction | BMC Medical Genetics | Full Text

Distribution of POLE mutations within the exonuclease domain. | Download  Scientific Diagram
Distribution of POLE mutations within the exonuclease domain. | Download Scientific Diagram

DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable  Immunodeficiency - ScienceDirect
DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency - ScienceDirect

POLE mutations improve the prognosis of endometrial cancer via regulating  cellular metabolism through AMF/AMFR signal transduction | BMC Medical  Genetics | Full Text
POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction | BMC Medical Genetics | Full Text

Genes | Free Full-Text | Risks at the DNA Replication Fork: Effects upon  Carcinogenesis and Tumor Heterogeneity | HTML
Genes | Free Full-Text | Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity | HTML

POLE proofreading defects: Contributions to mutagenesis and cancer. -  Abstract - Europe PMC
POLE proofreading defects: Contributions to mutagenesis and cancer. - Abstract - Europe PMC

Présentation PowerPoint
Présentation PowerPoint

Molecular profiling and sequential somatic mutation shift in hypermutator  tumours harbouring POLE mutations | Scientific Reports
Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations | Scientific Reports

Mutations in the POLE exonuclease domain in ECs. (A) Mutations in the... |  Download Scientific Diagram
Mutations in the POLE exonuclease domain in ECs. (A) Mutations in the... | Download Scientific Diagram

Concurrent genetic alterations in DNA polymerase proofreading and mismatch  repair in human colorectal cancer | European Journal of Human Genetics
Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer | European Journal of Human Genetics

POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its  Abundance, and Mismatch Repair Status - ScienceDirect
POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status - ScienceDirect

Mutational processes of distinct POLE exonuclease domain mutants drive an  enrichment of a specific TP53 mutation in colorectal cancer | PLOS Genetics
Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer | PLOS Genetics

Somatic POLE exonuclease domain mutations elicit enhanced intratumoral  immune responses in stage II colorectal cancer | Journal for ImmunoTherapy  of Cancer
Somatic POLE exonuclease domain mutations elicit enhanced intratumoral immune responses in stage II colorectal cancer | Journal for ImmunoTherapy of Cancer

Nivolumab Shows Promising Activity in Advanced Tumours with Rare
Nivolumab Shows Promising Activity in Advanced Tumours with Rare

Cancers | Free Full-Text | The TCGA Molecular Classification of Endometrial  Cancer and Its Possible Impact on Adjuvant Treatment Decisions | HTML
Cancers | Free Full-Text | The TCGA Molecular Classification of Endometrial Cancer and Its Possible Impact on Adjuvant Treatment Decisions | HTML

Church Group — Wellcome Centre for Human Genetics
Church Group — Wellcome Centre for Human Genetics

Exome sequencing reveals a de novo POLD1 mutation causing phenotypic  variability in mandibular hypoplasia, deafness, progeroid f
Exome sequencing reveals a de novo POLD1 mutation causing phenotypic variability in mandibular hypoplasia, deafness, progeroid f